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A CRISPR/Cas-Mediated Selection-free Knockin Strategy in Human Embryonic Stem Cells
The development of new gene-editing tools, in particular the CRISPR/Cas system, has greatly facilitated site-specific mutagenesis in human embryonic stem cells (hESCs), including the introduction or correction of patient-specific mutations for disease modeling. However, integration of a reporter gen...
Tallennettuna:
| Julkaisussa: | Stem Cell Reports |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Elsevier
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4471821/ https://ncbi.nlm.nih.gov/pubmed/26028531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.04.016 |
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