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An iCRISPR platform for rapid, multiplexable and inducible genome editing in human pluripotent stem cells

Human pluripotent stem cells (hPSCs) offer a unique platform for elucidating the genes and molecular pathways that underlie complex traits and diseases. To realize this promise, methods for rapid and controllable genetic manipulations are urgently needed. By combining two newly developed gene-editin...

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Bibliografische gegevens
Hoofdauteurs: González, Federico, Zhu, Zengrong, Shi, Zhong-Dong, Lelli, Katherine, Verma, Nipun, Li, Qing V., Huangfu, Danwei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127112/
https://ncbi.nlm.nih.gov/pubmed/24931489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.05.018
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