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An iCRISPR platform for rapid, multiplexable and inducible genome editing in human pluripotent stem cells
Human pluripotent stem cells (hPSCs) offer a unique platform for elucidating the genes and molecular pathways that underlie complex traits and diseases. To realize this promise, methods for rapid and controllable genetic manipulations are urgently needed. By combining two newly developed gene-editin...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4127112/ https://ncbi.nlm.nih.gov/pubmed/24931489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.05.018 |
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