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An iCRISPR platform for rapid, multiplexable and inducible genome editing in human pluripotent stem cells

Human pluripotent stem cells (hPSCs) offer a unique platform for elucidating the genes and molecular pathways that underlie complex traits and diseases. To realize this promise, methods for rapid and controllable genetic manipulations are urgently needed. By combining two newly developed gene-editin...

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Detalhes bibliográficos
Main Authors: González, Federico, Zhu, Zengrong, Shi, Zhong-Dong, Lelli, Katherine, Verma, Nipun, Li, Qing V., Huangfu, Danwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127112/
https://ncbi.nlm.nih.gov/pubmed/24931489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.05.018
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