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An iCRISPR platform for rapid, multiplexable and inducible genome editing in human pluripotent stem cells

Human pluripotent stem cells (hPSCs) offer a unique platform for elucidating the genes and molecular pathways that underlie complex traits and diseases. To realize this promise, methods for rapid and controllable genetic manipulations are urgently needed. By combining two newly developed gene-editin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: González, Federico, Zhu, Zengrong, Shi, Zhong-Dong, Lelli, Katherine, Verma, Nipun, Li, Qing V., Huangfu, Danwei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127112/
https://ncbi.nlm.nih.gov/pubmed/24931489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.05.018
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