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CRISPR/Cas-mediated knockin in human pluripotent stem cells

Fluorescent reporter and epitope tagged human pluripotent stem cells (hPSCs) greatly facilitate studies on the pluripotency and differentiation characteristics of these cells. Unfortunately traditional procedures to generate such lines are hampered by a low targeting efficiency that necessitates a l...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Verma, Nipun, Zhu, Zengrong, Huangfu, Danwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554709/
https://ncbi.nlm.nih.gov/pubmed/27807834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6539-7_9
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