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CRISPR/Cas-mediated knockin in human pluripotent stem cells

Fluorescent reporter and epitope tagged human pluripotent stem cells (hPSCs) greatly facilitate studies on the pluripotency and differentiation characteristics of these cells. Unfortunately traditional procedures to generate such lines are hampered by a low targeting efficiency that necessitates a l...

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Bibliografiske detaljer
Udgivet i:Methods Mol Biol
Main Authors: Verma, Nipun, Zhu, Zengrong, Huangfu, Danwei
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554709/
https://ncbi.nlm.nih.gov/pubmed/27807834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6539-7_9
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