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An iCRISPR platform for rapid, multiplexable and inducible genome editing in human pluripotent stem cells

Human pluripotent stem cells (hPSCs) offer a unique platform for elucidating the genes and molecular pathways that underlie complex traits and diseases. To realize this promise, methods for rapid and controllable genetic manipulations are urgently needed. By combining two newly developed gene-editin...

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Bibliografske podrobnosti
Main Authors: González, Federico, Zhu, Zengrong, Shi, Zhong-Dong, Lelli, Katherine, Verma, Nipun, Li, Qing V., Huangfu, Danwei
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4127112/
https://ncbi.nlm.nih.gov/pubmed/24931489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.05.018
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