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Reprogramming factor expression induces rapid and widespread targeted chromatin remodeling

Despite rapid progress in characterizing transcription factor-driven reprogramming of somatic cells to an induced pluripotent stem (iPS) cell state, many mechanistic questions still remain. To gain insight into the earliest events in the reprogramming process, we systematically analyzed the transcri...

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Detalhes bibliográficos
Main Authors: Koche, Richard P., Smith, Zachary D., Adli, Mazhar, Gu, Hongcang, Ku, Manching, Gnirke, Andreas, Bernstein, Bradley E., Meissner, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220622/
https://ncbi.nlm.nih.gov/pubmed/21211784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.12.001
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