Dissecting direct reprogramming through integrative genomic analysis

Somatic cells can be reprogrammed to a pluripotent state through the ectopic expression of defined transcription factors. Understanding the mechanism and kinetics of this transformation may shed light on the nature of developmental potency and suggest strategies with improved efficiency or safety. H...

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Bibliographic Details
Main Authors: Mikkelsen, Tarjei S., Hanna, Jacob, Zhang, Xiaolan, Ku, Manching, Wernig, Marius, Schorderet, Patrick, Bernstein, Bradley E., Jaenisch, Rudolf, Lander, Eric S., Meissner, Alexander
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754827/
https://ncbi.nlm.nih.gov/pubmed/18509334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07056
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