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Dissecting direct reprogramming through integrative genomic analysis

Somatic cells can be reprogrammed to a pluripotent state through the ectopic expression of defined transcription factors. Understanding the mechanism and kinetics of this transformation may shed light on the nature of developmental potency and suggest strategies with improved efficiency or safety. H...

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Detalles Bibliográficos
Main Authors: Mikkelsen, Tarjei S., Hanna, Jacob, Zhang, Xiaolan, Ku, Manching, Wernig, Marius, Schorderet, Patrick, Bernstein, Bradley E., Jaenisch, Rudolf, Lander, Eric S., Meissner, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754827/
https://ncbi.nlm.nih.gov/pubmed/18509334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07056
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