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A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
The study of induced pluripotency is complicated by the need for infection with high-titer retroviral vectors, which results in genetically heterogeneous cell populations. We generated genetically homogeneous ‘secondary’ somatic cells that carry the reprogramming factors as defined doxycycline (dox)...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654269/ https://ncbi.nlm.nih.gov/pubmed/18594521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt1483 |
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