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A single-gene transgenic mouse strain for reprogramming adult somatic cells
We report a novel transgenic mouse model for direct reprogramming of somatic cells by expressing four reprogramming factors from a single genomic locus using a drug-inducible transgene. Multiple somatic cell types explanted from different tissues can generate induced pluripotent stem cells (iPSC) by...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3048025/ https://ncbi.nlm.nih.gov/pubmed/20010831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1410 |
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