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Somatic cell reprogramming and transitions between pluripotent states: facts, hypotheses, unresolved issues
Direct reprogramming of somatic cells to induced pluripotent stem cells by ectopic expression of defined transcription factors has raised fundamental questions regarding the epigenetic stability of the differentiated cell state. In addition, evidence has accumulated that distinct states of pluripote...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3032267/ https://ncbi.nlm.nih.gov/pubmed/21074044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.10.008 |
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