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Somatic cell reprogramming and transitions between pluripotent states: facts, hypotheses, unresolved issues

Direct reprogramming of somatic cells to induced pluripotent stem cells by ectopic expression of defined transcription factors has raised fundamental questions regarding the epigenetic stability of the differentiated cell state. In addition, evidence has accumulated that distinct states of pluripote...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hanna, Jacob H., Saha, Krishanu, Jaenisch, Rudolf
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3032267/
https://ncbi.nlm.nih.gov/pubmed/21074044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.10.008
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