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Induced Pluripotency and Epigenetic Reprogramming

Induced pluripotency defines the process by which somatic cells are converted into induced pluripotent stem cells (iPSCs) upon overexpression of a small set of transcription factors. In this article, we put transcription factor–induced pluripotency into a historical context, review current methods t...

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Bibliographic Details
Published in:Cold Spring Harb Perspect Biol
Main Authors: Hochedlinger, Konrad, Jaenisch, Rudolf
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665075/
https://ncbi.nlm.nih.gov/pubmed/26626939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a019448
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