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Chromatin connections to pluripotency and cellular reprogramming

The pluripotent state of embryonic stem (ES) cells provides a unique perspective on regulatory programs that govern self-renewal and differentiation, and somatic cell reprogramming. Here we review the highly connected protein and transcriptional networks that maintain pluripotency, and how they are...

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Detalles Bibliográficos
Publicado en:Cell
Main Authors: Orkin, Stuart H., Hochedlinger, Konrad
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858411/
https://ncbi.nlm.nih.gov/pubmed/21663790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.05.019
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