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Transgenic Mice with Defined Combinations of Drug Inducible Reprogramming Factors
Drug-inducible lentiviruses encoding Oct4, Sox2, Klf4 and c-Myc were used to derive “primary” iPS cells and segregated through germline transmission generating mice and fibroblasts carrying subsets of the reprogramming factors. Drug treatment of the cells resulted in “secondary” iPS cell derivation...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654270/ https://ncbi.nlm.nih.gov/pubmed/19151700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1520 |
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