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Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors
Pluripotent cells can be derived from different types of somatic cells by nuclear reprogramming through the ectopic expression of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc. It is however unclear whether post-mitotic neurons are susceptible to direct reprogramming. Here we show that p...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3409465/ https://ncbi.nlm.nih.gov/pubmed/21563275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.641 |
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