Reprogramming of postnatal neurons into induced pluripotent stem cells by defined factors

Pluripotent cells can be derived from different types of somatic cells by nuclear reprogramming through the ectopic expression of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc. It is however unclear whether post-mitotic neurons are susceptible to direct reprogramming. Here we show that p...

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Detaylı Bibliyografya
Asıl Yazarlar: Kim, Jongpil, Lengner, Christopher J., Kirak, Oktay, Hanna, Jacob, Cassady, John P., Lodato, Michael A., Wu, Su, Faddah, Dina A., Steine, Eveline J., Gao, Qing, Fu, DongDong, Dawlaty, Meelad, Jaenisch, Rudolf
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409465/
https://ncbi.nlm.nih.gov/pubmed/21563275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.641
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