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Sequential expression of pluripotency markers during direct reprogramming of mouse somatic cells
Pluripotency can be induced in differentiated murine and human cells by retroviral transduction of Oct4, Sox2, Klf4 and c-Myc. We have devised a reprogramming strategy in which these four transcription factors are expressed from doxycycline (dox) inducible lentiviral vectors. Using these inducible c...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2276627/ https://ncbi.nlm.nih.gov/pubmed/18371436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.01.004 |
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