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Genome-scale DNA methylation maps of pluripotent and differentiated cells

DNA methylation is essential for normal development1–3 and has been implicated in many pathologies including cancer4,5. Our knowledge about the genome-wide distribution of DNA methylation, how it changes during cellular differentiation and how it relates to histone methylation and other chromatin mo...

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Bibliografske podrobnosti
Main Authors: Meissner, Alexander, Mikkelsen, Tarjei S., Gu, Hongcang, Wernig, Marius, Hanna, Jacob, Sivachenko, Andrey, Zhang, Xiaolan, Bernstein, Bradley E., Nusbaum, Chad, Jaffe, David B., Gnirke, Andreas, Jaenisch, Rudolf, Lander, Eric S.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896277/
https://ncbi.nlm.nih.gov/pubmed/18600261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07107
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