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High-throughput bisulfite sequencing in mammalian genomes

DNA methylation is a critical epigenetic mark that is essential for mammalian development and aberrant in many diseases including cancer. Over the past decade multiple methods have been developed and applied to characterize its genome-wide distribution. Of these, Reduced Representation Bisulfite Seq...

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Detalhes bibliográficos
Main Authors: Smith, Zachary D., Gu, Hongcang, Bock, Christoph, Gnirke, Andreas, Meissner, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864123/
https://ncbi.nlm.nih.gov/pubmed/19442738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.05.003
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