Gel-free multiplexed reduced representation bisulfite sequencing for large-scale DNA methylation profiling

Sequencing-based approaches have led to new insights about DNA methylation. While many different techniques for genome-scale mapping of DNA methylation have been employed, throughput has been a key limitation for most. To further facilitate the mapping of DNA methylation, we describe a protocol for...

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Detalhes bibliográficos
Main Authors: Boyle, Patrick, Clement, Kendell, Gu, Hongcang, Smith, Zachary D, Ziller, Michael, Fostel, Jennifer L, Holmes, Laurie, Meldrim, Jim, Kelley, Fontina, Gnirke, Andreas, Meissner, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491420/
https://ncbi.nlm.nih.gov/pubmed/23034176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-10-r92
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