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High-throughput bisulfite sequencing in mammalian genomes

DNA methylation is a critical epigenetic mark that is essential for mammalian development and aberrant in many diseases including cancer. Over the past decade multiple methods have been developed and applied to characterize its genome-wide distribution. Of these, Reduced Representation Bisulfite Seq...

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Détails bibliographiques
Auteurs principaux: Smith, Zachary D., Gu, Hongcang, Bock, Christoph, Gnirke, Andreas, Meissner, Alexander
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2864123/
https://ncbi.nlm.nih.gov/pubmed/19442738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2009.05.003
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