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Chromatin Profiling by Directly Sequencing Small Quantities of Immunoprecipitated DNA
Chromatin structure and transcription factor localization can be assayed genome-wide by sequencing genomic DNA fractionated by protein occupancy or other properties. However, current technologies involve multiple steps that introduce bias and inefficiency. Here we apply a single-molecule approach to...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862482/ https://ncbi.nlm.nih.gov/pubmed/19946276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1404 |
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