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Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state
Chromatin profiling provides a versatile means to investigate functional genomic elements and their regulation. However, current methods yield ensemble profiles that are insensitive to cell-to-cell variation. Here we combine microfluidics, DNA barcoding and sequencing to collect chromatin data at si...
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| Publicado no: | Nat Biotechnol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636926/ https://ncbi.nlm.nih.gov/pubmed/26458175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3383 |
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