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Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells

Hundreds of Chromatin Regulators (CRs) control chromatin structure and function by catalyzing and binding histone modifications, yet the rules governing these key processes remain obscure. Here, we present a systematic approach to infer CR function. We developed ChIP-string, a meso-scale assay that...

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Detalhes bibliográficos
Main Authors: Ram, Oren, Goren, Alon, Amit, Ido, Shoresh, Noam, Yosef, Nir, Ernst, Jason, Kellis, Manolis, Gymrek, Melissa, Issner, Robbyn, Coyne, Michael, Durham, Timothy, Zhang, Xiaolan, Donaghey, Julie, Epstein, Charles B., Regev, Aviv, Bernstein, Bradley E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312319/
https://ncbi.nlm.nih.gov/pubmed/22196736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.057
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