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Single-Molecule Decoding of Combinatorially-Modified Nucleosomes
Different combinations of histone modifications have been proposed to signal distinct gene regulatory functions, but are poorly addressed by existing technologies. Here, we apply high-throughput single-molecule imaging to decode combinatorial modifications on millions of individual nucleosomes from...
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| Publicat a: | Science |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4904710/ https://ncbi.nlm.nih.gov/pubmed/27151869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad7701 |
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