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Single-Molecule Decoding of Combinatorially-Modified Nucleosomes

Different combinations of histone modifications have been proposed to signal distinct gene regulatory functions, but are poorly addressed by existing technologies. Here, we apply high-throughput single-molecule imaging to decode combinatorial modifications on millions of individual nucleosomes from...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Science
Päätekijät: Shema, Efrat, Jones, Daniel, Shoresh, Noam, Donohue, Laura, Ram, Oren, Bernstein, Bradley E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4904710/
https://ncbi.nlm.nih.gov/pubmed/27151869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad7701
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