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Hematopoietic differentiation is required for initiation of acute myeloid leukemia
Mutations in acute myeloid leukemia (AML)-associated oncogenes often arise in hematopoietic stem cells (HSCs) and promote acquisition of leukemia stem cell (LSC) phenotypes. However, as LSCs often share features of lineage-restricted progenitors, the relative contribution of differentiation status t...
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| Gepubliceerd in: | Cell Stem Cell |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4636971/ https://ncbi.nlm.nih.gov/pubmed/26412561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.08.011 |
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