Requirement for CDK6 in MLL-rearranged acute myeloid leukemia

Chromosomal rearrangements involving the H3K4 methyltransferase mixed-lineage leukemia (MLL) trigger aberrant gene expression in hematopoietic progenitors and give rise to an aggressive subtype of acute myeloid leukemia (AML). Insights into MLL fusion-mediated leukemogenesis have not yet translated...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Placke, Theresa, Faber, Katrin, Nonami, Atsushi, Putwain, Sarah L., Salih, Helmut R., Heidel, Florian H., Krämer, Alwin, Root, David E., Barbie, David A., Krivtsov, Andrei V., Armstrong, Scott A., Hahn, William C., Huntly, Brian J., Sykes, Stephen M., Milsom, Michael D., Scholl, Claudia, Fröhling, Stefan
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2014
Teme:
Plenary Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190617/
https://ncbi.nlm.nih.gov/pubmed/24764564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-558114
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items