MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL

Acute lymphoblastic leukemia in infants (<1 year-of-age) is characterized by a high incidence of MLL rearrangements. Recently, direct targets of the MLL fusion protein have been identified. However, functional validation of the identified targets remained unacknowledged. In this study, we identif...

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Detalhes bibliográficos
Main Authors: van der Linden, Marieke H, Willekes, Merel, van Roon, Eddy, Seslija, Lidija, Schneider, Pauline, Pieters, Rob, Stam, Ronald W
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979919/
https://ncbi.nlm.nih.gov/pubmed/24736461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27757
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