MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL

Acute lymphoblastic leukemia in infants (<1 year-of-age) is characterized by a high incidence of MLL rearrangements. Recently, direct targets of the MLL fusion protein have been identified. However, functional validation of the identified targets remained unacknowledged. In this study, we identif...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: van der Linden, Marieke H, Willekes, Merel, van Roon, Eddy, Seslija, Lidija, Schneider, Pauline, Pieters, Rob, Stam, Ronald W
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2014
Gaiak:
Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979919/
https://ncbi.nlm.nih.gov/pubmed/24736461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27757
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