Identification of Genes Transcriptionally Responsive to the Loss of MLL Fusions in MLL-Rearranged Acute Lymphoblastic Leukemia

INTRODUCTION: MLL-rearranged acute lymphoblastic leukemia (ALL) in infants (<1 year) is characterized by high relapse rates and a dismal prognosis. To facilitate the discovery of novel therapeutic targets, we here searched for genes directly influenced by the repression of various MLL fusions. ME...

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Vydáno v:PLoS One
Hlavní autoři: van der Linden, Marieke H., Seslija, Lidija, Schneider, Pauline, Driessen, Emma M. C., Castro, Patricia Garrido, Stumpel, Dominique J. P. M., van Roon, Eddy, de Boer, Jasper, Williams, Owen, Pieters, Rob, Stam, Ronald W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368425/
https://ncbi.nlm.nih.gov/pubmed/25793396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120326
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