Identification of Genes Transcriptionally Responsive to the Loss of MLL Fusions in MLL-Rearranged Acute Lymphoblastic Leukemia

INTRODUCTION: MLL-rearranged acute lymphoblastic leukemia (ALL) in infants (<1 year) is characterized by high relapse rates and a dismal prognosis. To facilitate the discovery of novel therapeutic targets, we here searched for genes directly influenced by the repression of various MLL fusions. ME...

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Udgivet i:PLoS One
Main Authors: van der Linden, Marieke H., Seslija, Lidija, Schneider, Pauline, Driessen, Emma M. C., Castro, Patricia Garrido, Stumpel, Dominique J. P. M., van Roon, Eddy, de Boer, Jasper, Williams, Owen, Pieters, Rob, Stam, Ronald W.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4368425/
https://ncbi.nlm.nih.gov/pubmed/25793396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120326
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