MLL fusion-driven activation of CDK6 potentiates proliferation in MLL-rearranged infant ALL

Acute lymphoblastic leukemia in infants (<1 year-of-age) is characterized by a high incidence of MLL rearrangements. Recently, direct targets of the MLL fusion protein have been identified. However, functional validation of the identified targets remained unacknowledged. In this study, we identif...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: van der Linden, Marieke H, Willekes, Merel, van Roon, Eddy, Seslija, Lidija, Schneider, Pauline, Pieters, Rob, Stam, Ronald W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2014
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979919/
https://ncbi.nlm.nih.gov/pubmed/24736461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27757
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