Molecular and Cytogenetic Characteristics of Myeloid Malignancies Following Luminal Gastrointestinal Cancer

door Epstein-Peterson, Zachary D., Devlin, Sean M., Stein, Eytan M., Klimek, Virginia M., Saltz, Leonard B., Tallman, Martin S.
Gepubliceerd in Leuk Res (2019)

Maitake mushroom extract in myelodysplastic syndromes (MDS): a phase II study

door Wesa, Kathleen M., Cunningham-Rundles, Susanna, Klimek, Virginia M., Vertosick, Emily, Coleton, Marci I., Yeung, K. Simon, Lin, Hong, Nimer, Stephen, Cassileth, Barrie R.
Gepubliceerd in Cancer Immunol Immunother (2014)

Micafungin Versus Posaconazole Prophylaxis in Acute Leukemia or Myelodysplastic Syndrome: A Randomized Study

door Epstein, David J., Seo, Susan K., Huang, Yao-Ting, Park, Jay H., Klimek, Virginia M., Berman, Ellin, Tallman, Martin S., Frattini, Mark G., Papanicolaou, Genovefa A.
Gepubliceerd in J Infect (2018)

Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia

door Shih, Alan H., Chung, Stephen S., Dolezal, Emily K., Zhang, Su-Jiang, Abdel-Wahab, Omar I., Park, Christopher Y., Nimer, Stephen D., Levine, Ross L., Klimek, Virginia M.
Gepubliceerd in 2013

1-2-3 Project: A Quality Improvement Initiative to Normalize and Systematize Palliative Care for All Patients With Cancer in the Outpatient Clinic Setting

door Desai, Anjali V., Klimek, Virginia M., Chow, Kimberly, Epstein, Andrew S., Bernal, Camila, Anderson, Kelly, Okpako, Molly, Rawlins-Duell, Robin, Kramer, Dana, Romano, Danielle, Goldberg, Jessica I., Nelson, Judith E.
Gepubliceerd in J Oncol Pract (2018)

End-of-Life Care for Older AML Patients Relapsing after Allogeneic Stem Cell Transplant at a Dedicated Cancer Center

door Lin, Richard J., Elko, Theresa A., Perales, Miguel-Angel, Alexander, Koshy, Jakubowski, Ann A., Devlin, Sean M., Dahi, Parastoo B., Papadopoulos, Esperanza B., Klimek, Virginia M., Giralt, Sergio A., Nelson, Judith E.
Gepubliceerd in Bone Marrow Transplant (2018)

Progression of RAS-Mutant Leukemia during RAF Inhibitor Treatment

door Callahan, Margaret K., Rampal, Raajit, Harding, James J., Klimek, Virginia M., Chung, Young Rock, Merghoub, Taha, Wolchok, Jedd D., Solit, David B., Rosen, Neal, Abdel-Wahab, Omar, Levine, Ross L., Chapman, Paul B.
Gepubliceerd in 2012

Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells

door Kotini, Andriana G, Chang, Chan-Jung, Boussaad, Ibrahim, Delrow, Jeffrey J, Dolezal, Emily K, Nagulapally, Abhinav B, Perna, Fabiana, Fishbein, Gregory A, Klimek, Virginia M, Hawkins, R David, Huangfu, Danwei, Murry, Charles E, Graubert, Timothy, Nimer, Stephen D, Papapetrou, Eirini P
Gepubliceerd in Nat Biotechnol (2015)

Efficacy of Intermittent Combined RAF and MEK Inhibition in a Patient with Concurrent BRAF- and NRAS-Mutant Malignancies

door Abdel-Wahab, Omar, Klimek, Virginia M., Gaskell, Alisa A., Viale, Agnes, Cheng, Donavan, Kim, Eunhee, Rampal, Raajit, Bluth, Mark, Harding, James J., Callahan, Margaret K., Merghoub, Taha, Berger, Michael F., Solit, David B., Rosen, Neal, Levine, Ross L., Chapman, Paul B.
Gepubliceerd in Cancer Discov (2014)

Phase IIB Trial of Oral Midostaurin (PKC412), the FMS-Like Tyrosine Kinase 3 Receptor (FLT3) and Multi-Targeted Kinase Inhibitor, in Patients With Acute Myeloid Leukemia and High-R...

door Fischer, Thomas, Stone, Richard M., DeAngelo, Daniel J., Galinsky, Ilene, Estey, Elihu, Lanza, Carlo, Fox, Edward, Ehninger, Gerhard, Feldman, Eric J., Schiller, Gary J., Klimek, Virginia M., Nimer, Stephen D., Gilliland, D. Gary, Dutreix, Catherine, Huntsman-Labed, Alice, Virkus, Jodi, Giles, Francis J.
Gepubliceerd in 2010

The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal and leukemia cells

door Vu, Ly P., Pickering, Brian F., Cheng, Yuanming, Zaccara, Sara, Nguyen, Diu, Minuesa, Gerard, Chou, Timothy, Chow, Arthur, Saletore, Yogesh, MacKay, Matthew, Schulman, Jessica, Famulare, Christopher, Patel, Minal, Klimek, Virginia M., Garrett-Bakelman, Francine E., Melnick, Ari, Carroll, Martin, Mason, Christopher E., Jaffrey, Samie R., Kharas, Michael G.
Gepubliceerd in Nat Med (2017)

Mutational correlates of response to hypomethylating agent therapy in acute myeloid leukemia

door Coombs, Catherine C., Sallman, David A., Devlin, Sean M., Dixit, Shweta, Mohanty, Abhinita, Knapp, Kristina, Al Ali, Najla H., Lancet, Jeffrey E., List, Alan F., Komrokji, Rami S., Padron, Eric, Arcila, Maria E., Klimek, Virginia M., van den Brink, Marcel R. M., Tallman, Martin S., Levine, Ross L., Rampal, Raajit K., Rapaport, Franck
Gepubliceerd in Haematologica (2016)

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells

door Taggart, James, Ho, Tzu-Chieh, Amin, Elianna, Xu, Haiming, Barlowe, Trevor S., Perez, Alexendar R., Durham, Benjamin H., Tivnan, Patrick, Okabe, Rachel, Chow, Arthur, Vu, Ly, Park, Sun Mi, Prieto, Camila, Famulare, Christopher, Patel, Minal, Lengner, Christopher J., Verma, Amit, Roboz, Gail, Guzman, Monica, Klimek, Virginia M., Abdel-Wahab, Omar, Leslie, Christina, Nimer, Stephen D., Kharas, Michael G.
Gepubliceerd in Nat Commun (2016)

Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia

door Kotini, Andriana G, Chang, Chan-Jung, Chow, Arthur, Yuan, Han, Ho, Tzu-Chieh, Wang, Tiansu, Vora, Shailee, Solovyov, Alexander, Husser, Chrystel, Olszewska, Malgorzata, Teruya-Feldstein, Julie, Perumal, Deepak, Klimek, Virginia M, Spyridonidis, Alexandros, Rampal, Raajit K, Silverman, Lewis, Reddy, E Premkumar, Papaemmanuil, Elli, Parekh, Samir, Greenbaum, Benjamin D, Leslie, Christina S, Kharas, Michael G, Papapetrou, Eirini P
Gepubliceerd in Cell Stem Cell (2017)

Phase 3 results for vosaroxin/cytarabine in the subset of patients ≥60 years old with refractory/early relapsed acute myeloid leukemia

door Ravandi, Farhad, Ritchie, Ellen K., Sayar, Hamid, Lancet, Jeffrey E., Craig, Michael D., Vey, Norbert, Strickland, Stephen A., Schiller, Gary J., Jabbour, Elias, Pigneux, Arnaud, Horst, Heinz-August, Récher, Christian, Klimek, Virginia M., Cortes, Jorge E., Carella, Angelo-Michele, Egyed, Miklos, Krug, Utz, Fox, Judith A., Craig, Adam R., Ward, Renee, Smith, Jennifer A., Acton, Gary, Kantarjian, Hagop M., Stuart, Robert K.
Gepubliceerd in Haematologica (2018)

Vosaroxin plus cytarabine versus placebo plus cytarabine in patients with first relapsed or refractory acute myeloid leukaemia (VALOR): a randomised, controlled, double-blind, mult...

door Ravandi, Farhad, Ritchie, Ellen K., Sayar, Hamid, Lancet, Jeffrey E., Craig, Michael D., Vey, Norbert, Strickland, Stephen A., Schiller, Gary J., Jabbour, Elias, Erba, Harry P., Pigneux, Arnaud, Horst, Heinz-August, Recher, Christian, Klimek, Virginia M., Cortes, Jorge, Roboz, Gail J., Odenike, Olatoyosi, Thomas, Xavier, Havelange, Violaine, Maertens, Johan, Derigs, Hans-Günter, Heuser, Michael, Damon, Lloyd, Powell, Bayard L., Gaidano, Gianluca, Carella, Angelo-Michele, Wei, Andrew, Hogge, Donna, Craig, Adam R., Fox, Judith A., Ward, Renee, Smith, Jennifer A., Acton, Gary, Mehta, Cyrus, Stuart, Robert K., Kantarjian, Hagop M.
Gepubliceerd in Lancet Oncol (2015)

Cancer therapy shapes the fitness landscape of clonal hematopoiesis

door Bolton, Kelly L, Ptashkin, Ryan N, Gao, Teng, Braunstein, Lior, Devlin, Sean M, Kelly, Daniel, Patel, Minal, Berthon, Antonin, Syed, Aijazuddin, Yabe, Mariko, Coombs, Catherine C., Caltabellotta, Nicole M., Walsh, Mike, Offit, Kenneth, Stadler, Zsofia, Mandelker, Diana, Schulman, Jessica, Patel, Akshar, Philip, John, Bernard, Elsa, Gundem, Gunes, Ossa, Juan E Arango, Levine, Max, Martinez, Juan S Medina, Farnoud, Noushin, Glodzik, Dominik, Li, Sonya, Robson, Mark E, Lee, Choonsik, Pharoah, Paul D P, Stopsack, Konrad H, Spitzer, Barbara, Mantha, Simon, Fagin, James, Boucai, Laura, Gibson, Christopher J, Ebert, Benjamin L, Young, Andrew L, Druley, Todd, Takahashi, Koichi, Gillis, Nancy, Ball, Markus, Padron, Eric, Hyman, David M, Baselga, Jose, Norton, Larry, Gardos, Stuart, Klimek, Virginia M, Scher, Howard, Bajorin, Dean, Paraiso, Eder, Benayed, Ryma, Arcila, Maria E, Ladanyi, Marc, Solit, David B, Berger, Michael F, Tallman, Martin, Garcia-Closas, Montserrat, Chatterjee, Nilanjan, Diaz, Luis A, Levine, Ross L, Morton, Lindsay M, Zehir, Ahmet, Papaemmanuil, Elli
Gepubliceerd in Nat Genet (2020)