Cancer therapy shapes the fitness landscape of clonal hematopoiesis

Acquired mutations are pervasive across normal tissues. However, our understanding of the processes that drive transformation of certain clones to cancer is limited. Here we study this phenomenon in the context of clonal hematopoiesis (CH) and the development of therapy-related myeloid neoplasms (tM...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Genet
Autors principals: Bolton, Kelly L, Ptashkin, Ryan N, Gao, Teng, Braunstein, Lior, Devlin, Sean M, Kelly, Daniel, Patel, Minal, Berthon, Antonin, Syed, Aijazuddin, Yabe, Mariko, Coombs, Catherine C., Caltabellotta, Nicole M., Walsh, Mike, Offit, Kenneth, Stadler, Zsofia, Mandelker, Diana, Schulman, Jessica, Patel, Akshar, Philip, John, Bernard, Elsa, Gundem, Gunes, Ossa, Juan E Arango, Levine, Max, Martinez, Juan S Medina, Farnoud, Noushin, Glodzik, Dominik, Li, Sonya, Robson, Mark E, Lee, Choonsik, Pharoah, Paul D P, Stopsack, Konrad H, Spitzer, Barbara, Mantha, Simon, Fagin, James, Boucai, Laura, Gibson, Christopher J, Ebert, Benjamin L, Young, Andrew L, Druley, Todd, Takahashi, Koichi, Gillis, Nancy, Ball, Markus, Padron, Eric, Hyman, David M, Baselga, Jose, Norton, Larry, Gardos, Stuart, Klimek, Virginia M, Scher, Howard, Bajorin, Dean, Paraiso, Eder, Benayed, Ryma, Arcila, Maria E, Ladanyi, Marc, Solit, David B, Berger, Michael F, Tallman, Martin, Garcia-Closas, Montserrat, Chatterjee, Nilanjan, Diaz, Luis A, Levine, Ross L, Morton, Lindsay M, Zehir, Ahmet, Papaemmanuil, Elli
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891089/
https://ncbi.nlm.nih.gov/pubmed/33106634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-020-00710-0
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars