Femoral Bone Marrow Aspiration in Live Mice

Por Chung, Young Rock, Kim, Eunhee, Abdel-Wahab, Omar
Publicado em 2014

Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling

Por Chou, Wei Chin, Takeo, Makoto, Rabbani, Piul, Hu, Hai, Lee, Wendy, Chung, Young Rock, Carucci, John, Overbeek, Paul, Ito, Mayumi
Publicado em 2013

Progression of RAS-Mutant Leukemia during RAF Inhibitor Treatment

Por Callahan, Margaret K., Rampal, Raajit, Harding, James J., Klimek, Virginia M., Chung, Young Rock, Merghoub, Taha, Wolchok, Jedd D., Solit, David B., Rosen, Neal, Abdel-Wahab, Omar, Levine, Ross L., Chapman, Paul B.
Publicado em 2012

ASXL1 Mutations Promote Myeloid Transformation Through Loss of PRC2-Mediated Gene Repression

Por Abdel-Wahab, Omar, Adli, Mazhar, LaFave, Lindsay M., Gao, Jie, Hricik, Todd, Shih, Alan H., Pandey, Suveg, Patel, Jay, Chung, Young Rock, Koche, Richard, Perna, Fabiana, Zhao, Xinyang, Taylor, Jordan E., Park, Christopher Y., Carroll, Martin, Melnick, Ari, Nimer, Stephen D., Jaffe, Jacob D., Aifantis, Iannis, Bernstein, Bradley E., Levine, Ross L
Publicado em 2012

Hematopoietic Stem Cell Origin of BRAFV600E Mutations in Hairy Cell Leukemia

Por Chung, Stephen S., Kim, Eunhee, Park, Jae H., Chung, Young Rock, Lito, Piro, Teruya-Feldstein, Julie, Hu, Wenhuo, Beguelin, Wendy, Monette, Sebastien, Duy, Cihangir, Rampal, Raajit, Telis, Leon, Patel, Minal, Kim, Min Kyung, Huberman, Kety, Bouvier, Nancy, Berger, Michael F., Melnick, Ari M., Rosen, Neal, Tallman, Martin S., Park, Christopher Y., Abdel-Wahab, Omar
Publicado no Sci Transl Med (2014)

Modulation of splicing catalysis for therapeutic targeting of leukemias with spliceosomal mutations

Por Lee, Stanley Chun-Wei, Dvinge, Heidi, Kim, Eunhee, Cho, Hana, Micol, Jean-Baptiste, Chung, Young Rock, Durham, Benjamin H., Yoshimi, Akihide, Kim, Young Joon, Thomas, Michael, Lobry, Camille, Chen, Chun-Wei, Pastore, Alessandro, Taylor, Justin, Wang, Xujun, Krivtsov, Andrei, Armstrong, Scott A., Palacino, James, Buonamici, Silvia, Smith, Peter G., Bradley, Robert K., Abdel-Wahab, Omar
Publicado no Nat Med (2016)

Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms

Por Rampal, Raajit, Ahn, Jihae, Abdel-Wahab, Omar, Nahas, Michelle, Wang, Kai, Lipson, Doron, Otto, Geoff A., Yelensky, Roman, Hricik, Todd, McKenney, Anna Sophia, Chiosis, Gabriela, Chung, Young Rock, Pandey, Suveg, van den Brink, Marcel R. M., Armstrong, Scott A., Dogan, Ahmet, Intlekofer, Andrew, Manshouri, Taghi, Park, Christopher Y., Verstovsek, Srdan, Rapaport, Franck, Stephens, Philip J., Miller, Vincent A., Levine, Ross L.
Publicado no Proc Natl Acad Sci U S A (2014)

SRSF2 Mutations Contribute to Myelodysplasia Through Mutant-Specific Effects on Exon Recognition

Por Kim, Eunhee, Ilagan, Janine O., Liang, Yang, Daubner, Gerrit M., Lee, Stanley C.-W., Ramakrishnan, Aravind, Li, Yue, Chung, Young Rock, Micol, Jean-Baptiste, Murphy, Michele, Cho, Hana, Hana, Min-Kyung, Zebari, Ahmad S., Aumann, Shlomzion, Park, Christopher Y., Buonamici, Silvia, Smith, Peter G., Deeg, H. Joachim, Lobry, Camille, Aifantis, Iannis, Modis, Yorgo, Allain, Frederic H.-T., Halene, Stephanie, Bradley, Robert K., Abdel-Wahab, Omar
Publicado no Cancer Cell (2015)

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

Por Abdel-Wahab, Omar, Gao, Jie, Adli, Mazhar, Dey, Anwesha, Trimarchi, Thomas, Chung, Young Rock, Kuscu, Cem, Hricik, Todd, Ndiaye-Lobry, Delphine, LaFave, Lindsay M., Koche, Richard, Shih, Alan H., Guryanova, Olga A., Kim, Eunhee, Li, Sheng, Pandey, Suveg, Shin, Joseph Y., Telis, Leon, Liu, Jinfeng, Bhatt, Parva K., Monette, Sebastien, Zhao, Xinyang, Mason, Christopher E., Park, Christopher Y., Bernstein, Bradley E., Aifantis, Iannis, Levine, Ross L.
Publicado em 2013

Prevention of dietary fat-fueled ketogenesis attenuates BRAF V600E tumor growth

Por Xia, Siyuan, Lin, Ruiting, Jin, Lingtao, Zhao, Liang, Kang, Hee-Bum, Pan, Yaozhu, Liu, Shuangping, Qian, Guoqing, Qian, Zhiyu, Konstantakou, Evmorfia, Zhang, Baotong, Dong, Jin-Tang, Chung, Young Rock, Abdel-Wahab, Omar, Merghoub, Taha, Zhou, Lu, Kudchadkar, Ragini R., Lawson, David H., Khoury, Hanna J., Khuri, Fadlo R., Boise, Lawrence H., Lonial, Sagar, Lee, Benjamin H., Pollack, Brian P., Arbiser, Jack L., Fan, Jun, Lei, Qun-Ying, Chen, Jing
Publicado no Cell Metab (2017)

Loss of BAP1 function leads to EZH2-dependent transformation

Por LaFave, Lindsay M., Béguelin, Wendy, Koche, Richard, Teater, Matt, Spitzer, Barbara, Chramiec, Alan, Papalexi, Efthymia, Keller, Matthew D., Hricik, Todd, Konstantinoff, Katerina, Micol, Jean-Baptiste, Durham, Benjamin, Knutson, Sarah K., Campbell, John E., Blum, Gil, Shi, Xinxu, Doud, Emma H., Krivtsov, Andrei V., Chung, Young Rock, Khodos, Inna, de Stanchina, Elisa, Ouerfelli, Ouathek, Adusumilli, Prasad S., Thomas, Paul M., Kelleher, Neil L., Luo, Minkui, Keilhack, Heike, Abdel-Wahab, Omar, Melnick, Ari, Armstrong, Scott A., Levine, Ross L.
Publicado no Nat Med (2015)

EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation

Por Béguelin, Wendy, Popovic, Relja, Teater, Matt, Jiang, Yanwen, Bunting, Karen L., Rosen, Monica, Shen, Hao, Yang, Shao Ning, Wang, Ling, Ezponda, Teresa, Martinez-Garcia, Eva, Zhang, Haikuo, Zhang, Yupeng, Verma, Sharad K., McCabe, Michael T., Ott, Heidi M., Van Aller, Glenn S., Kruger, Ryan G., Liu, Yan, McHugh, Charles F., Scott, David W., Chung, Young Rock, Kelleher, Neil, Shaknovich, Rita, Creasy, Caretha L., Gascoyne, Randy D., Wong, Kwok-Kin, Cerchietti, Leandro C., Levine, Ross L., Abdel-Wahab, Omar, Licht, Jonathan D., Elemento, Olivier, Melnick, Ari M.
Publicado em 2013

Targeting Mutant BRAF with Vemurafenib in Relapsed or Refractory Hairy Cell Leukemia

Por Tiacci, Enrico, Park, Jae H., De Carolis, Luca, Chung, Stephen S., Broccoli, Alessandro, Scott, Sasinya, Zaja, Francesco, Devlin, Sean, Pulsoni, Alessandro, Chung, Young Rock, Cimminiello, Michele, Kim, Eunhee, Rossi, Davide, Stone, Richard M., Motta, Giovanna, Saven, Alan, Varettoni, Marzia, Altman, Jessica K., Anastasia, Antonella, Grever, Michael R., Ambrosetti, Achille, Rai, Kanti R., Fraticelli, Vincenzo, Lacouture, Mario E., Carella, Angelo Michele, Levine, Ross L., Leoni, Pietro, Rambaldi, Alessandro, Falzetti, Franca, Ascani, Stefano, Capponi, Monia, Martelli, Maria Paola, Park, Christopher Y., Pileri, Stefano Aldo, Rosen, Neal, Foà, Robin, Berger, Michael F., Zinzani, Pier Luigi, Abdel-Wahab, Omar, Falini, Brunangelo, Tallman, Martin S.
Publicado no N Engl J Med (2015)