Prevention of dietary fat-fueled ketogenesis attenuates BRAF V600E tumor growth

Lifestyle factors including diet play an important role in the survival of cancer patients. However, the molecular mechanisms underlying pathogenic links between diet and particular oncogenic mutations in human cancers remain unclear. We recently reported that the ketone body acetoacetate selectivel...

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Publicado no:Cell Metab
Main Authors: Xia, Siyuan, Lin, Ruiting, Jin, Lingtao, Zhao, Liang, Kang, Hee-Bum, Pan, Yaozhu, Liu, Shuangping, Qian, Guoqing, Qian, Zhiyu, Konstantakou, Evmorfia, Zhang, Baotong, Dong, Jin-Tang, Chung, Young Rock, Abdel-Wahab, Omar, Merghoub, Taha, Zhou, Lu, Kudchadkar, Ragini R., Lawson, David H., Khoury, Hanna J., Khuri, Fadlo R., Boise, Lawrence H., Lonial, Sagar, Lee, Benjamin H., Pollack, Brian P., Arbiser, Jack L., Fan, Jun, Lei, Qun-Ying, Chen, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299059/
https://ncbi.nlm.nih.gov/pubmed/28089569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2016.12.010
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