HMG-CoA synthase 1 is a synthetic lethal partner of BRAF(V600E) in human cancers

Contributions of metabolic changes to cancer development and maintenance have received increasing attention in recent years. Although many human cancers share similar metabolic alterations, it remains unclear whether oncogene-specific metabolic alterations are required for tumor development. Using a...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Zhao, Liang, Fan, Jun, Xia, Siyuan, Pan, Yaozhu, Liu, Shuangping, Qian, Guoqing, Qian, Zhiyu, Kang, Hee-Bum, Arbiser, Jack L., Pollack, Brian P., Kudchadkar, Ragini R., Lawson, David H., Rossi, Michael, Abdel-Wahab, Omar, Merghoub, Taha, Khoury, Hanna J., Khuri, Fadlo R., Boise, Lawrence H., Lonial, Sagar, Chen, Fangping, Chen, Jing, Lin, Ruiting
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2017
Konular:
Metabolism
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473220/
https://ncbi.nlm.nih.gov/pubmed/28468827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.788778
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