Tetrameric acetyl-CoA acetyltransferase 1 is important for tumor growth

Mitochondrial acetyl-CoA acetyltransferase 1 (ACAT1) regulates pyruvate dehydrogenase complex (PDC) by acetylating pyruvate dehydrogenase (PDH) and PDH phosphatase. How ACAT1 is “hijacked” to contribute to the Warburg effect in human cancer remains unclear. We found that active, tetrameric ACAT1 is...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cell
Päätekijät: Fan, Jun, Lin, Ruiting, Xia, Siyuan, Chen, Dong, Elf, Shannon E., Liu, Shuangping, Pan, Yaozhu, Xu, Haidong, Qian, Zhiyu, Wang, Mei, Shan, Changliang, Zhou, Lu, Lei, Qun-Ying, Li, Yuancheng, Mao, Hui, Lee, Benjamin H., Sudderth, Jessica, DeBerardinis, Ralph J., Zhang, Guojing, Owonikoko, Taofeek, Gaddh, Manila, Arellano, Martha L., Khoury, Hanna J., Khuri, Fadlo R., Kang, Sumin, Doetsch, Paul W., Lonial, Sagar, Boggon, Titus J., Curran, Walter J., Chen, Jing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135630/
https://ncbi.nlm.nih.gov/pubmed/27867011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.10.014
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia