γ-6-phosphogluconolactone, a byproduct of the oxidative pentose phosphate pathway, contributes to AMPK activation through inhibition of PP2A

The oxidative pentose phosphate pathway (oxiPPP) contributes to cell metabolism through not only the production of metabolic intermediates and reductive NADPH, but also inhibition of LKB1-AMPK signaling by ribulose-5-phosphate (Ru-5-P), the product of the third oxiPPP enzyme 6-phosphogluconate dehyd...

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Gao, Xue, Zhao, Liang, Liu, Shuangping, Li, Yuancheng, Xia, Siyuan, Chen, Dong, Wang, Mei, Wu, Shaoxiong, Dai, Qing, Vu, Hieu, Zacharias, Lauren, DeBerardinis, Ralph, Lim, Esther, Metallo, Christian, Boggon, Titus J., Lonial, Sagar, Lin, Ruiting, Mao, Hui, Pan, Yaozhu, Shan, Changliang, Chen, Jing
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925637/
https://ncbi.nlm.nih.gov/pubmed/31586547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.09.007
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