Efficacy of treatment for acneiform eruptions related to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) for non-small cell lung cancer (NSCLC): A protocol...

Por He, Canfeng, Lin, Ruiting, Zhang, Jing, Sun, Lingling, Lin, Jietao, Lin, Lizhu
Publicado no Medicine (Baltimore) (2021)

Acetylation Stabilizes ATP-Citrate Lyase to Promote Lipid Biosynthesis and Tumor Growth

Por Lin, Ruiting, Tao, Ren, Gao, Xue, Li, Tingting, Zhou, Xin, Guan, Kun-Liang, Xiong, Yue, Lei, Qun-Ying
Publicado em 2013

Network pharmacology based research into the effect and mechanism of Yinchenhao Decoction against Cholangiocarcinoma

Por Chen, Zhiqiang, Lin, Tong, Liao, Xiaozhong, Li, Zeyun, Lin, Ruiting, Qi, Xiangjun, Chen, Guoming, Sun, Lingling, Lin, Lizhu
Publicado no Chin Med (2021)

Acetylation Targets the M2 Isoform of Pyruvate Kinase for Degradation through Chaperone-Mediated Autophagy and Promotes Tumor Growth

Por Lv, Lei, Li, Dong, Zhao, Di, Lin, Ruiting, Chu, Yajing, Zhang, Heng, Zha, Zhengyu, Liu, Ying, Li, Zi, Xu, Yanping, Wang, Gang, Huang, Yiran, Xiong, Yue, Guan, Kun-Liang, Lei, Qun-Ying
Publicado no Mol Cell (2011)

Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to anti-malarial agent dihydroartemisinin

Por Elf, Shannon, Lin, Ruiting, Xia, Siyuan, Pan, Yaozhu, Shan, Changliang, Wu, Shaoxiong, Lonial, Sagar, Gaddh, Manila, Arellano, Martha L., Khoury, Hanna J., Khuri, Fadlo R., Lee, Benjamin H., Boggon, Titus J., Fan, Jun, Chen, Jing
Publicado no Oncogene (2016)

Tyr-301 Phosphorylation Inhibits Pyruvate Dehydrogenase by Blocking Substrate Binding and Promotes the Warburg Effect

Por Fan, Jun, Kang, Hee-Bum, Shan, Changliang, Elf, Shannon, Lin, Ruiting, Xie, Jianxin, Gu, Ting-Lei, Aguiar, Mike, Lonning, Scott, Chung, Tae-Wook, Arellano, Martha, Khoury, Hanna J., Shin, Dong M., Khuri, Fadlo R., Boggon, Titus J., Kang, Sumin, Chen, Jing
Publicado em 2014

Dietary supplement chondroitin-4-sulfate exhibits oncogene-specific pro-tumor effects on BRAF V600E melanoma cells

Por Lin, Ruiting, Xia, Siyuan, Shan, Changliang, Chen, Dong, Liu, Yijie, Gao, Xue, Wang, Mei, Kang, Hee-Bum, Pan, Yaozhu, Liu, Shuangping, Chung, Young Rock, Abdel-Wahab, Omar, Merghoub, Taha, Rossi, Michael, Kudchadkar, Ragini R., Lawson, David H., Khuri, Fadlo R., Lonial, Sagar, Chen, Jing
Publicado no Mol Cell (2018)

γ-6-phosphogluconolactone, a byproduct of the oxidative pentose phosphate pathway, contributes to AMPK activation through inhibition of PP2A

Por Gao, Xue, Zhao, Liang, Liu, Shuangping, Li, Yuancheng, Xia, Siyuan, Chen, Dong, Wang, Mei, Wu, Shaoxiong, Dai, Qing, Vu, Hieu, Zacharias, Lauren, DeBerardinis, Ralph, Lim, Esther, Metallo, Christian, Boggon, Titus J., Lonial, Sagar, Lin, Ruiting, Mao, Hui, Pan, Yaozhu, Shan, Changliang, Chen, Jing
Publicado no Mol Cell (2019)

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

Por Wang, Jing, Luo, Cheng, Shan, Changliang, You, Qiancheng, Lu, Junyan, Elf, Shannon, Zhou, Yu, Wen, Yi, Vinkenborg, Jan L., Fan, Jun, Kang, Heebum, Lin, Ruiting, Han, Dali, Xie, Yuxin, Karpus, Jason, Chen, Shijie, Ouyang, Shisheng, Luan, Chihao, Zhang, Naixia, Ding, Hong, Merkx, Maarten, Liu, Hong, Chen, Jing, Jiang, Hualiang, He, Chuan
Publicado no Nat Chem (2015)

HMG-CoA synthase 1 is a synthetic lethal partner of BRAF(V600E) in human cancers

Por Zhao, Liang, Fan, Jun, Xia, Siyuan, Pan, Yaozhu, Liu, Shuangping, Qian, Guoqing, Qian, Zhiyu, Kang, Hee-Bum, Arbiser, Jack L., Pollack, Brian P., Kudchadkar, Ragini R., Lawson, David H., Rossi, Michael, Abdel-Wahab, Omar, Merghoub, Taha, Khoury, Hanna J., Khuri, Fadlo R., Boise, Lawrence H., Lonial, Sagar, Chen, Fangping, Chen, Jing, Lin, Ruiting
Publicado no J Biol Chem (2017)

Mutant and wild-type isocitrate dehydrogenase 1 share enhancing mechanisms involving distinct tyrosine kinase cascades in cancer

Por Chen, Dong, Xia, Siyuan, Wang, Mei, Lin, Ruiting, Li, Yuancheng, Mao, Hui, Aguiar, Mike, Famulare, Christopher A., Shih, Alan H., Brennan, Cameron W., Gao, Xue, Pan, Yaozhu, Liu, Shuangping, Fan, Jun, Jin, Lingtao, Song, Lina, Zhou, An, Mukherjee, Joydeep, Pieper, Russell O., Mishra, Ashutosh, Peng, Junmin, Arellano, Martha, Blum, William G., Lonial, Sagar, Boggon, Titus J., Levine, Ross L., Chen, Jing
Publicado no Cancer Discov (2019)

Tetrameric acetyl-CoA acetyltransferase 1 is important for tumor growth

Por Fan, Jun, Lin, Ruiting, Xia, Siyuan, Chen, Dong, Elf, Shannon E., Liu, Shuangping, Pan, Yaozhu, Xu, Haidong, Qian, Zhiyu, Wang, Mei, Shan, Changliang, Zhou, Lu, Lei, Qun-Ying, Li, Yuancheng, Mao, Hui, Lee, Benjamin H., Sudderth, Jessica, DeBerardinis, Ralph J., Zhang, Guojing, Owonikoko, Taofeek, Gaddh, Manila, Arellano, Martha L., Khoury, Hanna J., Khuri, Fadlo R., Kang, Sumin, Doetsch, Paul W., Lonial, Sagar, Boggon, Titus J., Curran, Walter J., Chen, Jing
Publicado no Mol Cell (2016)

Prevention of dietary fat-fueled ketogenesis attenuates BRAF V600E tumor growth

Por Xia, Siyuan, Lin, Ruiting, Jin, Lingtao, Zhao, Liang, Kang, Hee-Bum, Pan, Yaozhu, Liu, Shuangping, Qian, Guoqing, Qian, Zhiyu, Konstantakou, Evmorfia, Zhang, Baotong, Dong, Jin-Tang, Chung, Young Rock, Abdel-Wahab, Omar, Merghoub, Taha, Zhou, Lu, Kudchadkar, Ragini R., Lawson, David H., Khoury, Hanna J., Khuri, Fadlo R., Boise, Lawrence H., Lonial, Sagar, Lee, Benjamin H., Pollack, Brian P., Arbiser, Jack L., Fan, Jun, Lei, Qun-Ying, Chen, Jing
Publicado no Cell Metab (2017)

Lysine acetylation activates 6-phosphogluconate dehydrogenase to promote tumor growth

Por Shan, Changliang, Elf, Shannon, Ji, Quanjiang, Kang, Hee-Bum, Zhou, Lu, Hitosugi, Taro, Jin, Lingtao, Lin, Ruiting, Zhang, Liang, Seo, Jae Ho, Xie, Jianxin, Tucker, Meghan, Gu, Ting-Lei, Sudderth, Jessica, Jiang, Lei, DeBerardinis, Ralph J., Wu, Shaoxiong, Li, Yuancheng, Mao, Hui, Chen, Peng, Wang, Dongsheng, Chen, Georgia Zhuo, Lonial, Sagar, Arellano, Martha L., Khoury, Hanna J., Khuri, Fadlo R., Lee, Benjamin H., Brat, Daniel J., Ye, Keqiang, Boggon, Titus J., He, Chuan, Kang, Sumin, Fan, Jun, Chen, Jing
Publicado em 2014

Metabolic rewiring by oncogenic BRAF V600E links ketogenesis pathway to BRAF-MEK1 signaling

Por Kang, Hee-Bum, Fan, Jun, Lin, Ruiting, Elf, Shannon, Ji, Quanjiang, Zhao, Liang, Jin, Lingtao, Seo, Jae Ho, Shan, Changliang, Arbiser, Jack L., Cohen, Cynthia, Brat, Daniel, Miziorko, Henry M., Kim, Eunhee, Abdel-Wahab, Omar, Merghoub, Taha, Fröhling, Stefan, Scholl, Claudia, Tamayo, Pablo, Barbie, David A., Zhou, Lu, Pollack, Brian P., Fisher, Kevin, Kudchadkar, Ragini R., Lawson, David H., Sica, Gabriel, Rossi, Michael, Lonial, Sagar, Khoury, Hanna J., Khuri, Fadlo R., Lee, Benjamin H., Boggon, Titus J., He, Chuan, Kang, Sumin, Chen, Jing
Publicado no Mol Cell (2015)

6-phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumor growth by inhibiting LKB1-AMPK signaling

Por Lin, Ruiting, Elf, Shannon, Shan, Changliang, Kang, Hee-Bum, Ji, Quanjiang, Zhou, Lu, Hitosugi, Taro, Zhang, Liang, Zhang, Shuai, Ho Seo, Jae, Xie, Jianxin, Tucker, Meghan, Gu, Ting-Lei, Sudderth, Jessica, Jiang, Lei, Mitsche, Matthew, DeBerardinis, Ralph J., Wu, Shaoxiong, Li, Yuancheng, Mao, Hui, Chen, Peng R., Wang, Dongsheng, Chen, Georgia Zhuo, Hurwitz, Selwyn J., Lonial, Sagar, Khoury, Hanna J., Arellano, Martha L., Khoury, Hanna J., Khuri, Fadlo R., Lee, Benjamin H., Lei, Qunying, Brat, Daniel J., Ye, Keqiang, Boggon, Titus J., He, Chuan, Kang, Sumin, Fan, Jun, Chen, Jing
Publicado no Nat Cell Biol (2015)