Auto-Inhibition of Ets-1 Is Counteracted by DNA Binding Cooperativity with Core-Binding Factor α2

od Goetz, Tamara L., Gu, Ting-Lei, Speck, Nancy A., Graves, Barbara J.
Izdano 2000

Auto-Inhibition and Partner Proteins, Core-Binding Factor β (CBFβ) and Ets-1, Modulate DNA Binding by CBFα2 (AML1)

od Gu, Ting-Lei, Goetz, Tamara L., Graves, Barbara J., Speck, Nancy A.
Izdano 2000

Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific mass spectromet...

od Kasyapa, Chitta, Gu, Ting-Lei, Natarajan, Lalitha, Polakiewicz, Roberto, Cowell, John K
Izdano 2009

Epidermal Growth Factor Stimulates RSK2 Activation through Activation of the MEK/ERK Pathway and Src-dependent Tyrosine Phosphorylation of RSK2 at Tyr-529

od Kang, Sumin, Dong, Shaozhong, Guo, Ailan, Ruan, Hong, Lonial, Sagar, Khoury, Hanna Jean, Gu, Ting-Lei, Chen, Jing
Izdano 2007

14–3-3 integrates prosurvival signals mediated by the AKT and MAPK pathways in ZNF198-FGFR1–transformed hematopoietic cells

od Dong, Shaozhong, Kang, Sumin, Gu, Ting-Lei, Kardar, Sean, Fu, Haian, Lonial, Sagar, Khoury, Hanna Jean, Khuri, Fadlo, Chen, Jing
Izdano 2007

Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs

od Mohi, M. Golam, Boulton, Christina, Gu, Ting-Lei, Sternberg, David W., Neuberg, Donna, Griffin, James D., Gilliland, D. Gary, Neel, Benjamin G.
Izdano 2004

Profiling Y561-Dependent and -Independent Substrates of CSF-1R in Epithelial Cells

od Knowlton, Melodie L., Selfors, Laura M., Wrobel, Carolyn N., Gu, Ting-Lei, Ballif, Bryan A., Gygi, Steven P., Polakiewicz, Roberto, Brugge, Joan S.
Izdano 2010

Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells

od Tam, Winnie F., Gu, Ting-Lei, Chen, Jing, Lee, Benjamin H., Bullinger, Lars, Fröhling, Stefan, Wang, Andrew, Monti, Stefano, Golub, Todd R., Gilliland, D. Gary
Izdano 2008

Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling

od Pighi, Chiara, Gu, Ting-Lei, Dalai, Irene, Barbi, Stefano, Parolini, Claudia, Bertolaso, Anna, Pedron, Serena, Parisi, Alice, Ren, Jianmin, Cecconi, Daniela, Chilosi, Marco, Menestrina, Fabio, Zamò, Alberto
Izdano 2011

FGFR3 Activates RSK2 to Mediate Hematopoietic Transformation through Tyrosine Phosphorylation of RSK2 and Activation of the MEK/ERK Pathway

od Kang, Sumin, Dong, Shaozhong, Gu, Ting-Lei, Guo, Ailan, Cohen, Michael S., Lonial, Sagar, Khoury, Hanna Jean, Fabbro, Doriano, Gary Gilliland, D., Leif Bergsagel, P., Taunton, Jack, Polakiewicz, Roberto D., Chen, Jing
Izdano 2007

JAK2T875N is a novel activating mutation that results in myeloproliferative disease with features of megakaryoblastic leukemia in a murine bone marrow transplantation model

od Mercher, Thomas, Wernig, Gerlinde, Moore, Sandra A., Levine, Ross L., Gu, Ting-Lei, Fröhling, Stefan, Cullen, Dana, Polakiewicz, Roberto D., Bernard, Olivier A., Boggon, Titus J., Lee, Benjamin H., Gilliland, D. Gary
Izdano 2006

Tyrosine Phosphorylation of Lactate Dehydrogenase A Is Important for NADH/NAD(+) Redox Homeostasis in Cancer Cells

od Fan, Jun, Hitosugi, Taro, Chung, Tae-Wook, Xie, Jianxin, Ge, Qingyuan, Gu, Ting-Lei, Polakiewicz, Roberto D., Chen, Georgia Z., Boggon, Titus J., Lonial, Sagar, Khuri, Fadlo R., Kang, Sumin, Chen, Jing
Izdano 2011

Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles

od Matheny, Christina J, Speck, Maren E, Cushing, Patrick R, Zhou, Yunpeng, Corpora, Takeshi, Regan, Michael, Newman, Miki, Roudaia, Liya, Speck, Caroline L, Gu, Ting-Lei, Griffey, Stephen M, Bushweller, John H, Speck, Nancy A
Izdano 2007

Survey of Activated FLT3 Signaling in Leukemia

od Gu, Ting-lei, Nardone, Julie, Wang, Yi, Loriaux, Marc, Villén, Judit, Beausoleil, Sean, Tucker, Meghan, Kornhauser, Jon, Ren, Jianmin, MacNeill, Joan, Gygi, Steven P., Druker, Brian J., Heinrich, Michael C., Rush, John, Polakiewicz, Roberto D.
Izdano 2011

Tyr-94 Phosphorylation Inhibits Pyruvate Dehydrogenase Phosphatase 1 and Promotes Tumor Growth

od Shan, Changliang, Kang, Hee-Bum, Elf, Shannon, Xie, Jianxin, Gu, Ting-Lei, Aguiar, Mike, Lonning, Scott, Hitosugi, Taro, Chung, Tae-Wook, Arellano, Martha, Khoury, Hanna J., Shin, Dong M., Khuri, Fadlo R., Boggon, Titus J., Fan, Jun
Izdano 2014

A novel fusion of RBM6 to CSF1R in acute megakaryoblastic leukemia

od Gu, Ting-lei, Mercher, Thomas, Tyner, Jeffrey W., Goss, Valerie L., Walters, Denise K., Cornejo, Melanie G., Reeves, Cynthia, Popova, Lana, Lee, Kimberly, Heinrich, Michael C., Rush, John, Daibata, Masanori, Miyoshi, Isao, Gilliland, D. Gary, Druker, Brian J., Polakiewicz, Roberto D.
Izdano 2007

Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism

od Hitosugi, Taro, Fan, Jun, Chung, Tae-Wook, Lythgoe, Katherine, Wang, Xu, Xie, Jianxin, Ge, Qingyuan, Gu, Ting-Lei, Polakiewicz, Roberto D., Roesel, Johannes L., Chen, Zhuo (Georgia), Boggon, Titus J., Lonial, Sagar, Fu, Haian, Khuri, Fadlo R., Kang, Sumin, Chen, Jing
Izdano 2011

The Prometastatic Ribosomal S6 Kinase 2-cAMP Response Element-binding Protein (RSK2-CREB) Signaling Pathway Up-regulates the Actin-binding Protein Fascin-1 to Promote Tumor Metasta...

od Li, Dan, Jin, Lingtao, Alesi, Gina N., Kim, Young-Mee, Fan, Jun, Seo, Jae Ho, Wang, Dongsheng, Tucker, Meghan, Gu, Ting-Lei, Lee, Benjamin H., Taunton, Jack, Magliocca, Kelly R., Chen, Zhuo G., Shin, Dong M., Khuri, Fadlo R., Kang, Sumin
Izdano 2013

Tyr-301 Phosphorylation Inhibits Pyruvate Dehydrogenase by Blocking Substrate Binding and Promotes the Warburg Effect

od Fan, Jun, Kang, Hee-Bum, Shan, Changliang, Elf, Shannon, Lin, Ruiting, Xie, Jianxin, Gu, Ting-Lei, Aguiar, Mike, Lonning, Scott, Chung, Tae-Wook, Arellano, Martha, Khoury, Hanna J., Shin, Dong M., Khuri, Fadlo R., Boggon, Titus J., Kang, Sumin, Chen, Jing
Izdano 2014

Fibroblast Growth Factor Receptor 3 Associates with and Tyrosine Phosphorylates p90 RSK2, Leading to RSK2 Activation That Mediates Hematopoietic Transformation

od Kang, Sumin, Elf, Shannon, Dong, Shaozhong, Hitosugi, Taro, Lythgoe, Katherine, Guo, Ailan, Ruan, Hong, Lonial, Sagar, Khoury, Hanna J., Williams, Ifor R., Lee, Benjamin H., Roesel, Johannes L., Karsenty, Gerard, Hanauer, André, Taunton, Jack, Boggon, Titus J., Gu, Ting-Lei, Chen, Jing
Izdano 2009