Id1 is a common downstream target of oncogenic tyrosine kinases in leukemic cells

Oncogenic tyrosine kinases, such as BCR-ABL, TEL-ABL, TEL-PDGFβR, and FLT3-ITD, play a major role in the development of hematopoietic malignancy. They activate many of the same signal transduction pathways. To identify the critical target genes required for transformation in hematopoietic cells, we...

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Detalhes bibliográficos
Main Authors: Tam, Winnie F., Gu, Ting-Lei, Chen, Jing, Lee, Benjamin H., Bullinger, Lars, Fröhling, Stefan, Wang, Andrew, Monti, Stefano, Golub, Todd R., Gilliland, D. Gary
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518899/
https://ncbi.nlm.nih.gov/pubmed/18559972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-07-103010
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