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Auto-Inhibition of Ets-1 Is Counteracted by DNA Binding Cooperativity with Core-Binding Factor α2

Auto-inhibition is a common transcriptional control mechanism that is well characterized in the regulatory transcription factor Ets-1. Autoinhibition of Ets-1 DNA binding works through an inhibitory module that exists in two conformations. DNA binding requires a change in the inhibitory module from...

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Udgivet i:Mol Cell Biol
Principais autores: Goetz, Tamara L., Gu, Ting-Lei, Speck, Nancy A., Graves, Barbara J.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85055/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594011/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.81-90.2000
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