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The Leukemic Protein Core Binding Factor β (CBFβ)–Smooth-Muscle Myosin Heavy Chain Sequesters CBFα2 into Cytoskeletal Filaments and Aggregates

The fusion gene CBFB-MYH11 is generated by the chromosome 16 inversion associated with acute myeloid leukemias. This gene encodes a chimeric protein involving the core binding factor β (CBFβ) and the smooth-muscle myosin heavy chain (SMMHC). Mouse model studies suggest that this chimeric protein CBF...

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Bibliografske podrobnosti
Main Authors: Adya, Neeraj, Stacy, Terryl, Speck, Nancy A., Liu, Pu Paul
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC109324/
https://ncbi.nlm.nih.gov/pubmed/9819429
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