The Leukemic Protein Core Binding Factor β (CBFβ)–Smooth-Muscle Myosin Heavy Chain Sequesters CBFα2 into Cytoskeletal Filaments and Aggregates

The fusion gene CBFB-MYH11 is generated by the chromosome 16 inversion associated with acute myeloid leukemias. This gene encodes a chimeric protein involving the core binding factor β (CBFβ) and the smooth-muscle myosin heavy chain (SMMHC). Mouse model studies suggest that this chimeric protein CBF...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Adya, Neeraj, Stacy, Terryl, Speck, Nancy A., Liu, Pu Paul
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1998
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.12.7432
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