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Multimerization via Its Myosin Domain Facilitates Nuclear Localization and Inhibition of Core Binding Factor (CBF) Activities by the CBFβ-Smooth Muscle Myosin Heavy Chain Myeloid Leukemia Oncoprotein
In CBFβ-SMMHC, core binding factor beta (CBFβ) is fused to the α-helical rod domain of smooth muscle myosin heavy chain (SMMHC). We generated Ba/F3 hematopoietic cells expressing a CBFβ-SMMHC variant lacking 28 amino acids homologous to the assembly competence domain (ACD) required for multimerizati...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC134059/ https://ncbi.nlm.nih.gov/pubmed/12417730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8278-8291.2002 |
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