Multimerization via Its Myosin Domain Facilitates Nuclear Localization and Inhibition of Core Binding Factor (CBF) Activities by the CBFβ-Smooth Muscle Myosin Heavy Chain Myeloid Leukemia Oncoprotein

In CBFβ-SMMHC, core binding factor beta (CBFβ) is fused to the α-helical rod domain of smooth muscle myosin heavy chain (SMMHC). We generated Ba/F3 hematopoietic cells expressing a CBFβ-SMMHC variant lacking 28 amino acids homologous to the assembly competence domain (ACD) required for multimerizati...

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Detalles Bibliográficos
Main Authors: Kummalue, Tanawan, Lou, Jianrong, Friedman, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC134059/
https://ncbi.nlm.nih.gov/pubmed/12417730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.23.8278-8291.2002
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