The Leukemic Protein Core Binding Factor β (CBFβ)–Smooth-Muscle Myosin Heavy Chain Sequesters CBFα2 into Cytoskeletal Filaments and Aggregates

The fusion gene CBFB-MYH11 is generated by the chromosome 16 inversion associated with acute myeloid leukemias. This gene encodes a chimeric protein involving the core binding factor β (CBFβ) and the smooth-muscle myosin heavy chain (SMMHC). Mouse model studies suggest that this chimeric protein CBF...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Mol Cell Biol
Autori principali:	Adya, Neeraj, Stacy, Terryl, Speck, Nancy A., Liu, Pu Paul
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1998
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109324/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9819429/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.12.7432
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!