Inhibition of KIT Tyrosine Kinase Activity: Two Decades After the First Approval

Por Klug, Lillian R., Corless, Christopher L., Heinrich, Michael C.
Publicado no J Clin Oncol (2021)

Early and Next-Generation KIT/PDGFRA Kinase Inhibitors and the Future of Treatment for Advanced Gastrointestinal Stromal Tumor

Por Bauer, Sebastian, George, Suzanne, von Mehren, Margaret, Heinrich, Michael C.
Publicado no Front Oncol (2021)

Quadruple wild-type (WT) GIST: defining the subset of GIST that lacks abnormalities of KIT, PDGFRA, SDH, or RAS signaling pathways

Por Pantaleo, Maria A, Nannini, Margherita, Corless, Christopher L, Heinrich, Michael C
Publicado no Cancer Med (2015)

Ectodermally derived steel/stem cell factor functions non–cell autonomously during primitive erythropoiesis in Xenopus

Por Goldman, Devorah C., Berg, Linnea K., Heinrich, Michael C., Christian, Jan L.
Publicado em 2006

Ménétrier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach

Por Coffey, Robert J., Washington, Mary Kay, Corless, Christopher L., Heinrich, Michael C.
Publicado em 2007

KIT Mutations Are Common in Incidental Gastrointestinal Stromal Tumors One Centimeter or Less in Size

Por Corless, Christopher L., McGreevey, Laura, Haley, Andrea, Town, Ajia, Heinrich, Michael C.
Publicado em 2002

Survival in advanced GIST has improved over time and correlates with increased access to post-imatinib tyrosine kinase inhibitors: results from Life Raft Group Registry

Por Call, Jerry W., Wang, Yu, Montoya, Denisse, Scherzer, Norman J., Heinrich, Michael C.
Publicado no Clin Sarcoma Res (2019)

Correction to: Survival in advanced GIST has improved over time and correlates with increased access to post-imatinib tyrosine kinase inhibitors: results from Life Raft Group Regis...

Por Call, Jerry W., Wang, Yu, Montoya, Denisse, Scherzer, Norman J., Heinrich, Michael C.
Publicado no Clin Sarcoma Res (2019)

Quantifying Membrane Curvature Generation of Drosophila Amphiphysin N-BAR Domains

Por Heinrich, Michael C., Capraro, Benjamin R., Tian, Aiwei, Isas, Jose M., Langen, Ralf, Baumgart, Tobias
Publicado em 2010

A smooth muscle-derived, BRAF-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin

Por Kondo, Jumpei, Huh, Won Jae, Franklin, Jeffrey L, Heinrich, Michael C, Rubin, Brian P, Coffey, Robert J
Publicado no J Pathol (2020)

Combination Therapy for KIT-Mutant Mast Cells: Targeting Constitutive NFAT and KIT Activity

Por Macleod, Alison C., Klug, Lillian R., Patterson, Janice, Griffith, Diana J., Beadling, Carol, Town, Ajia, Heinrich, Michael C.
Publicado no Mol Cancer Ther (2014)

KIT Gene Mutations in Gastrointestinal Stromal Tumors : More Complex than Previously Recognized?

Por Fletcher, Jonathan A., Fletcher, Christopher D.M., Rubin, Brian P., Ashman, Leonie K., Corless, Christopher L., Heinrich, Michael C.
Publicado em 2002

KIT Gene Deletions at the Intron 10−Exon 11 Boundary in GI Stromal Tumors

Por Corless, Christopher L., McGreevey, Laura, Town, Ajia, Schroeder, Arin, Bainbridge, Troy, Harrell, Patina, Fletcher, Jonathan A., Heinrich, Michael C.
Publicado em 2004

Allele-Specific Polymerase Chain Reaction for the Imatinib-Resistant KIT D816V and D816F Mutations in Mastocytosis and Acute Myelogenous Leukemia

Por Corless, Christopher L., Harrell, Patina, Lacouture, Mario, Bainbridge, Troy, Le, Claudia, Gatter, Ken, White, Clifton, Granter, Scott, Heinrich, Michael C.
Publicado em 2006

Clinical efficacy comparison of avapritinib with other tyrosine kinase inhibitors in gastrointestinal stromal tumors with PDGFRA D842V mutation: a retrospective analysis of clinica...

Por von Mehren, Margaret, Heinrich, Michael C., Shi, Hongliang, Iannazzo, Sergio, Mankoski, Raymond, Dimitrijević, Saša, Hoehn, Gerard, Chiroli, Silvia, George, Suzanne
Publicado no BMC Cancer (2021)

SDHC methylation in gastrointestinal stromal tumors (GIST): a case report

Por Urbini, Milena, Astolfi, Annalisa, Indio, Valentina, Heinrich, Michael C., Corless, Christopher L., Nannini, Margherita, Ravegnini, Gloria, Biasco, Guido, Pantaleo, Maria A.
Publicado no BMC Med Genet (2015)

Gene expression of the IGF pathway family distinguishes subsets of gastrointestinal stromal tumors wild type for KIT and PDGFRA

Por Beadling, Carol, Patterson, Janice, Justusson, Emily, Nelson, Dylan, Pantaleo, Maria A., Hornick, Jason L., Chacón, Matias, Corless, Christopher L., Heinrich, Michael C.
Publicado em 2013

Mitotic recombination as evidence of alternative pathogenesis of gastrointestinal stromal tumours in neurofibromatosis type 1

Por Stewart, Douglas R, Corless, Christopher L, Rubin, Brian P, Heinrich, Michael C, Messiaen, Ludwine M, Kessler, Lisa J, Zhang, Paul J, Brooks, David G
Publicado em 2007

KIT Mutations Are Common in Testicular Seminomas

Por Kemmer, Kathleen, Corless, Christopher L., Fletcher, Jonathan A., McGreevey, Laura, Haley, Andrea, Griffith, Diana, Cummings, Oscar W., Wait, Cecily, Town, Ajia, Heinrich, Michael C.
Publicado em 2004

The multi-targeted receptor tyrosine kinase inhibitor, Linifanib (ABT-869), induces apoptosis through an AKT and Glycogen Synthase Kinase 3β-dependent pathway

Por Hernandez-Davies, Jenny E., Zape, Joan P., Landaw, Elliot M., Tan, Xiaolin, Presnell, Ajia, Griffith, Diana, Heinrich, Michael C., Glaser, Keith B, Sakamoto, Kathleen M
Publicado em 2011